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DNA diets don't work

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Weight loss similar with healthy low-fat, low-carbohydrate diets

The Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) randomized clinical trial lasted 12 months and included 609 adults aged 18 to 50 years without diabetes who had a body mass index (BMI) between 28 and 40, which generally generally indicates that the individual is slightly overweight to borderline extremely obese, although BMI is not a ideal measure of a healthy weight. You might also know of someone who had weight loss success on one of these diets and another who didn't lose a single pound.

While metabolic and genomic testing aren't good indicators of how efficiently a body loses weight, the researchers warned that in the future, there might be new research that'll bring up better predictors of which diets work best for a person.

"One both sides, we heard from people who had lost the most weight that we had helped them change their relationship to food, and that now they were more thoughtful about how they ate".

The team enlisted 609 participants between the ages of 18 and 50. which were divided into two equally-sized groups. The other group went low-fat, starting with no more than 20 grams of fat per day, the equivalent to a handful of nuts.

After the second month, they were instructed to make incremental adjustments as needed, adding back 5-15 grams of fat or carbs gradually and aiming to reach a balance they believed could be maintained for the rest of their lives.

However, the researchers did note that some of the results did differ greatly, with some people losing around 60 pounds and others gaining around 20 pounds.

Participants were randomly assigned to the 12-month healthy low-fat diet (n = 305) or healthy low-carbohydrate diet (n = 304); both diets were delivered by health educators during 22 diet-specific small group sessions that focused on methods for achieving the lowest fat or carbohydrate intake.

During the first 8 weeks, participants were told to limit their daily carbohydrate or fat intake to just 20g, the equivalent of a slice and a half of bread.

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Before they embarked on the study, each participant had part of their genome sequenced and their baseline insulin outputs measured.

Gardener said: "We made sure to tell everybody, regardless of which diet they were on, to go to the farmer's market, and don't buy processed convenience food crap". But blood type diets have also been shown to be of dubious use.

But who lost weight and how much had nearly nothing to do with their genetic pattern or which diet they were on, Gardner and colleagues found.

By the end of the study, individuals in the two groups had lost, on average, 13 pounds.

Further, enormous weight loss variability was observed among the participants of both the groups.

Additionally, the scientists found that there were no significant diet-insulin or diet-genotype interactions. They plan to look at whether a person's microbiome or gene expression finally solves the mystery.

For you the reader, the biggest takeaways would be that there isn't a clear-cut victor between low-fat and low-carb. In fact it's not the diet that you should be mindful of, but your body. "People who ate plenty of vegetables and whole foods lost significant amounts of weight over the course of the year without restricting the quantity of food that they consumed, according to a new study published in JAMA on Tuesday". "But let's cut to the chase: We didn't replicate that study, we didn't even come close".

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