Apr 18 2018
Gandhi explained that the reason non-small cell lung cancer is so deadly is the existing chemotherapy drugs provide only limited survival benefits for patients. It seems that the only condition for this therapy to work is to treat cancer patients before they have surgery.
"What it suggests is that chemotherapy alone is no longer a standard of care", said Dr. Leena Gandhi, who led the study. The findings of the study revealed that when Keytruda was administered alongside standard chemotherapy, the risk of death or having the cancer become worse was cut in half compared to chemotherapy alone after nearly a year. It can be given for up to 24 months for those without disease progression, Merck said. This is a huge progress that will certainly help lung cancer patients a lot more.
Immunotherapy, which harnesses the body's immune system to attack tumors, is known to improve survival in patients who have already been treated with chemo.
Pembrolizumab, sold under the brand name Keytruda, is an FDA-approved drug sold by a subsidiary of Merck & Company, Inc. that sponsored this study.
One group of 400 patients received standard chemotherapy and the immunotherapy drug pembrolizumab, while a smaller group of patients received chemotherapy.
Athletic therapist dies after Humboldt bus crash, raising death toll to 16
She graduated in 2016 with a bachelor of Kinesiology at the University of Regina , according to the school . However, the family is asking for privacy from media and will not be responding to interview requests.
Toys R Us receives several $1bn bids for its Asia unit
Moorfields has been managing the administration of the bust company, after it was unable to pay a 15 million pound tax bill. Failed US toy-store chain Toys'R'Us reportedly plans to sell its Asia business for more than one billion dollars.
Cambridge Analytica denies using data of Indians
Facing his second day of questioning from members of Congress on Wednesday, Zuckerberg was answering a question from Rep. Facebook said it learned of Cambridge Analytica's violation in 2015, and was told by the firm that the data was deleted.
According to the study, Merck's immunotherapy drug fared very well in a lung cancer trial for people with advanced non-squamous NSCLC, increasing survival rates to 69.2 percent when coupled with chemotherapy.
The study, which tested treatment effectiveness and side effects, included 616 patients at 118 medical facilities across the world.
"The differences were not small", says Gandhi.
For non-squamous non-small cell lung cancer patients, median survival with chemotherapy alone is somewhere around 11 or 12 months, he said.
The study participants were divided into two groups: one group received only the chemotherapy drug, while the other was administered an additional 200 mg of pembrolizumab every three weeks, for the duration of four treatment cycles. "But it works. It's wonderful that we're going to be bringing these drugs to the majority of patients with lung cancer in the first-line setting", Herbst added.
"The addition of pembrolizumab to chemotherapy resulted in significantly higher rates of response and longer progression-free survival than chemotherapy alone", her team writes in their paper. Then, they underwent the surgery they needed for their type of the disease, lung cancer. "We do need to focus more on how to differentiate the patients who will get the most benefit".
Apr 18 2018
Harley Quinn Movie Hires Female Director
Yan, whose feature-film debut Dead Pigs picked up an award at Sundance this year, beat out numerous contenders for the plum job. Warner Bros. has been hard at work on developing a slew of films based on DC properties over the past few years.
Apr 18 2018
Mourinho wants strong Manchester United finish to secure second place
Jose Mourinho has ruled out bringing in another striker this summer, with Manchester United already well-stocked up front. It has emerged though that Lukaku will likely play on Sunday against West Brom in the league.
Apr 17 2018
Montenegro elects pro-West president Milo Djukanovic, projections show
He came under investigation and was indicted by prosecutors in the Italian city of Bari in 2008 for alleged tobacco smuggling. His main opponent is Mladen Bojanić, a businessman supported by several parties, including pro-Russian contingents.
Apr 16 2018
Corbyn Questions Legal Basis for British Strikes in Syria
She added: "We agreed that it was both right and legal to take military action together with our closest allies". Clearly not when we are under attack or the Prime Minister has been kidnapped, or anything like that".
Apr 16 2018
Trump says Syria strikes "perfectly executed", declares "Mission Accomplished!"
Mrs May will make the statement explaining why she ordered British cruise missile strikes and will then take questions from MPs. Security Council on Saturday that the U.S. was "locked and loaded" should Assad use poison gas on his own people again.
Apr 15 2018
BioShock Revival Rumored To Be Underway At New "Top-Secret" 2K Studio
However, the issue is that Parkside is not ready to bring a lot of Hangar 13 people over to work on the upcoming BioShock . However, a hand full setup shop in the studio next door and is supposedly working on a yet to be announced BioShock game.
Apr 14 2018
National Basketball Association playoffs preview: Who's playing who in the East and West
John Wall has played in just four games since January 27, and the Wizards have oddly looked better without the star point guard. With coach Nate McMillan and All-Star guard Victor Oladipo leading the way, the Pacers were a wonderful surprise this season.
Apr 14 2018
E. coli outbreak now in 11 states
New Jersey has identified six E. coli cases in Somerset, Hunterdon, Middlesex and Warren counties that may be linked to Panera. The states that reported cases of infection are New Jersey, Idaho, Connecticut, Pennsylvania, Missouri, Ohio, and Washington.
Apr 13 2018
Saudi Aramco picks up 50% stake in Maharashtra refinery
However, B Ashok, the CEO of RRPL, reportedly claimed that the project is well on its course and is expected to be ready by 2025. The new facility will be integrated with an existing oil refinery-itself a joint venture between Aramco and Total.
Apr 13 2018
Sanders slams Trump's proposal to rejoin Trans-Pacific Partnership
Trump told CNBC in an interview in Davos, Switzerland that he "would do TPP, if we made a much better deal than we had". Farm state lawmakers have pushed for greater sales of the higher ethanol blend to boost demand for the corn-based fuel.
Apr 18 2018OPCW chemical weapons inspectors enter Douma - Syrian state media
Apr 17 2018Don't delay: Tuesday is Tax Day
Apr 17 2018Police officer fatally shot while serving arrest warrant
Apr 15 2018Colorado Senator Releases Statement On Marijuana Policy
Apr 14 2018Afghanistan: Taliban attack kills 10 security forces in Herat
Apr 13 2018Trump Keeps His Syria Attack Options Open as Russia Urges Calm
Apr 13 2018Marvel's Avengers: Infinity War Gets A New Featurette About Family
Apr 13 2018US Still Assessing Intel on Alleged Douma Chemical Attack - Mattis
Apr 12 2018Local Doctors Push For Organ Donations During National Donate Life Month
Apr 12 2018Florida Gov. Rick Scott Announces Senate Run
Apr 18 2018Busch passes Larson to win at Bristol
Apr 18 2018FIFA Charges World Cup Host Russia for Fan Racism
Apr 16 2018Carrie Underwood Shares First Up-Close Face Photo Since Accident
Apr 16 2018Congress' first candidates list out, Siddaramaiah to contest from Chamundeshwari
Apr 15 2018Trump attorney is focus of 'monthslong' investigation into personal dealings
Apr 15 2018IPL: AB de Villiers smashes 57 to help RCB beat Kings
Apr 14 2018Klopp confident Salah will stay with Reds
Apr 13 2018Almost 260 dead in military plane crash in Algeria
Apr 12 2018Uber launches new revamped Uber Driver app in India
Apr 12 2018Real Offer Cash Plus Player For Salah
Apr 12 2018Alleged Toronto serial killer now charged with seven counts of first-degree murder
Apr 12 2018Walmart Brings Online Grocery Deliveries to Charlotte, NC