Oct 02 2018
Congratulations to MD Anderson Cancer Center's Dr. Jim Allison, who has jointly won the 2018 Nobel Prize in Physiology or Medicine for his immunotherapy research.
The discoveries by Allison, 70, and Honjo, 76, "absolutely paved the way for a new approach to cancer treatment", Dr. Jedd Wolchok, chief of the melanoma and immunotherapeutics service at the Memorial Sloan Kettering Cancer Center in NY, told The Associated Press.
Allison's crucial insight was to block a protein on T cells that acts as a brake on their activation, freeing the T cells to attack cancer.
The Nobel Committee members said they are hopeful that combinations of these drugs and other therapies will allow more cancer patients to benefit with fewer side effects.
T-cells are a type of white blood cell that play a central role in the body's natural immunity to disease.
Their work, on stimulating the body's immune system to attack tumours, have produced "strikingly effective" therapies, the Nobel Assembly of Sweden's Karolinska Institute said.
"A driving motivation for scientists is simply to push the frontiers of knowledge", Allison said in a written statement released by the MD Anderson Cancer Center.
In a statement to reporters after learning of his award, Allison said he was "honored and humbled". "They are living proof of the power of basic science", he added.
Liverpool's Mohamed Salah 'fine' despite lack of goals - Jurgen Klopp
Manolo Gabbiadini will also be absent as a lower hamstring injury will keep him out of the sixth Premier League gameweek. The German continued: " He is a top professional and his body gives him the opportunity to do so ".
Nuno: Wolves will stick to their guns at Manchester United
And Jimenez says competition among the squad is strong, which is helping the players to perform well on the pitch. They've spent money, they have style and they play with no fear.
Amazon could open 3,000 cashierless Go stores by 2021
Amazon is mulling a plan to open as many as 3,000 cashierless food stores over the next three years, according to a media report. Sleek black cameras monitoring from above and weight sensors in the shelves help Amazon determine exactly what people take.
Honjo, who is now 76, told a news conference in Tokyo he was honored to get the Nobel, but that his work was not yet done.
Honjo, of Kyoto University, discovered a new protein, the ligand PD-1, which also acted as a brake on immune cells.
The Nobel jury said that "for more than 100 years, scientists attempted to engage the immune system in the fight against cancer".
"Until the seminal discoveries by the two laureates, progress into clinical development was modest", the release stated. Just last week, such a drug was approved for treatment of another kind of skin cancer called squamous cell cancer, he said.
The discoveries led to the creation of a multibillion-dollar market for new cancer medicines.
Allison's drug, known commercially as Yervoy, became the first to extend the survival of patients with late-stage melanoma.
U.S. drugmakers Merck & Co and Bristol-Myers Squibb now lead the field after winning drug approvals in 2014, but Roche, AstraZeneca, Pfizer and Sanofi are also fielding rivals.
Medicine is the first of the Nobel Prizes awarded each year.
Oct 02 2018
Elon Musk Resigns As Chairman Of Telsa
In emails leaked to CNBC , Musk hinted that Tesla was " very close " to being profitable and told staff to " ignore the distractions ".
Sep 29 2018
Pogba makes gesture to photographer after clashing Mourinho in training
You will find Jose Mourinho's players being managers all over the place because he has been so successful in his career. But after the penalty shootout defeat, defender Young told MUTV : "I think they had more intensity than we did".
Sep 28 2018
Will change mind if allegations against Kavanaugh credible
Brett Kavanaugh came out swinging against Democrats in a remarkable opening statement during Thursday's historic Senate hearing. She continued: "I wouldn't characterize him as not friendly - he was just nervous and not really wanting to speak with me".
Sep 27 2018
Klopp unhappy with use of VAR in Chelsea loss
Alli sealed a 4-2 penalty shootout after a lively finish saw the game end 2-2 after 90 minutes, with extra time not being played in the competition.
Sep 24 2018
Ted Cruz meets with voters in Webster
When asked by the hosts of "The View" about his fans' reaction to him headlining for O'Rourke, Nelson replied "I don't care". It is the first of three debates in what's shaping up to be one of the most interesting election races in the country.
Sep 24 2018
Washington Redskins: 3 Standouts from Week 2 vs. Colts
Playing with two bad legs, No. 12 manages to drive his team down the field for 75 yards and a touchdown to open the half. Both players could pose problems for the Packers and it will be interesting to see if Josh Jackson is deployed on Reed.
Sep 24 2018
Thursday hearing for Kavanaugh accuser stuck on last details
Ford accused Kavanaugh of assaulting her 36 years ago when the two were in high school. Kavanaugh has denied the allegation and pledged to testify at Monday's hearing.
Sep 21 2018
Jack Ma kills 1m US jobs promise, blaming US-China trade war
The tariffs imposed by the USA are set to come into effect from September 24 with the 10% level, which will be increased to 25% from next year.
Sep 20 2018
Coca-Cola Could Make A Move Into CBD-Infused Drinks
Coca-Cola has been engaged in talks with Canadian marijuana producer Aurora Cannabis to develop the beverages, Bloomberg said. As beverage makers including Molson Coors step into the marijuana market, Coca-Cola is thinking about joining the pot party.
Sep 20 2018
From amps to microwaves, Amazon tipped to reveal more Alexa devices
Should we expect to see Amazon try to make more home devices smart? Some of the devices will also have Alexa built in. Alexa is Amazon's virtual assistant, which competes with Google Assistant.
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